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A multidimensional study on the exploration of the biological rhythm between man and nature based on the intraocular pressure curve (clinical part)

Phase 1
Conditions
primary open angle glaucoma
Registration Number
ITMCTR2022000063
Lead Sponsor
Eye Hospital, Chinese Academy of Chinese Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) Diagnosed as primary open-angle glaucoma;
(2) TCM syndrome differentiation belongs to Jueyin disease Wumei Pill syndrome;
(3) Age 18 to 80 years old;
(4) 24h intraocular pressure fluctuation range =8mmHg;
(5) The corrected visual acuity of both eyes is greater than or equal to 0.1, and there are no other eye diseases and drugs (such as ocular trauma, retinal diseases, hormones, etc.) that may cause increased intraocular pressure and other factors that may increase the error of intraocular pressure measurement (leukoplakia, proptosis, etc.) Wait);
(6) Be able to understand and be willing to receive treatment in accordance with the research protocol, and be able to follow-up consultations as required;
(7) Sign the informed consent.

Exclusion Criteria

(1) Patients who do not meet the inclusion criteria;
(2) Patients with severe cardiovascular and cerebrovascular diseases, serious diseases such as liver and kidney, hematopoietic system, and mental illness;
(3) Pregnant or lactating women;
(4) Participating in other clinical trials;
(5) Can not cooperate with this research.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
24h intraocular pressure; field of view;
Secondary Outcome Measures
NameTimeMethod
Hydrocortisone,CORT;vision;(Pittsburgh sleep quality index,PSQI;Depression Anxiety Stress Scale 21,DASS-21;raditional Chinese medicine Syndrome Scale;Athens Insomnia Scale,AIS;melatonin,MT;
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