NL-OMON49325招募中不适用
Early cognitive, social and neural mechanisms that precede clinical onset of ASD in a community sample - Early mechanisms of autism
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 2 至 11（—）
入选标准
- •High-risk infants
- •Age between 18 months and 24 months old
- •At least one of the parents understands and speaks Dutch
- •Positive screen on the Communication and Social development Signals (CoSoS)
- •(with a score >=3)
- •Caregiver and/or well-baby office professional (doctor, nurse) has ASD-specific
- •concerns about their child
- •Low-risk infants
- •Age between 18 months and 24 months old
- •At least one of the parents understands and speaks Dutch
- •Negativescreen on the Communication and Social development Signals (CoSoS)
- •(with a score <3)
- •Caregiver and/or professional does not have any ASD-specific concerns about the
排除标准
- •High-risk infants
- •Diagnosis of epilepsy or history of fits/convulsions in infant (not including
- •febrile convulsions);
- •Known presence of genetic syndrome (in proband or infant) clearly related to
- •ASD (e.g. TSC, FXS, 22q11, 16p11.2, Rett*s)
- •Presence of known significant uncorrected vision or hearing impairment in
- •infant (reported to parent by a doctor or health care professional)
- •Infant was born prematurely (pre 36 weeks)
- •Infant is looked after by the state (e.g. foster care), or other situation in
- •which neither birth parent is involved in the infant*s care.
- •Low-risk infants
- •Diagnosis of epilepsy or history of fits/convulsions in infant;
- •Known presence of genetic syndrome (in proband or infant) clearly related to
- •ASD (e.g. TSC, FXS, 22q11, 16p11.2, Rett*s)
- •Presence of known significant uncorrected vision or hearing impairment in
- •infant (reported to parent by a doctor or health care professional)
- •Infant was born prematurely (pre 36 weeks)
- •Infant is looked after by the state (e.g. foster care), or other situation in
- •which neither birth parent is involved in the infant*s care.
- •Presence of known significant developmental or medical condition in infant
- •likely to affect brain development or infant*s ability to participate in the
- •study (e.g. Cerebral Palsy, Down*s syndrome, cystic fibrosis)
- •Presence of ASD in 1st degree relatives
研究者
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