Paracetamol treatment in hypertension: effect on blood pressure - The PATH-BP study

niversity of Edinburgh0 个研究点目标入组 110 人开始时间: 2013年12月4日最近更新: 2020年2月1日

适应症

试验速览

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•=18 years old, men or post-menopausal women. Half of the patients recruited will be women (to allow PG measurement). Treated hypertensive patients with an average daytime ABPM <150/95mmHg on stable doses of one or more antihypertensive medication (at least one of which should be; an ACEi, ARB or diuretic) for 3 months, or untreated hypertensive patients with an average daytime ABPM =135/85 but <150/95.
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 70
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 40

•History of ischaemic heart disease, cardiac failure, cerebrovascular disease, liver impairment (ALT/AST>50IU/L) or stage 3-5 chronic kidney disease. Patients with a history of overdose or suicidal ideation. Patients weighing <55kgs. Patients with chronic pain requiring treatment, with a known allergy to paracetamol, or concomitant use of NSAIDs, oral anticoagulants or corticosteroids.

发起方

niversity of Edinburgh