NL-OMON51539
Recruiting
Not Applicable
The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderly - BLUEBERRY
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- high blood pressure
- Sponsor
- Radboud Universitair Medisch Centrum
- Enrollment
- 12
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Age \>\=70 years.
- •\- Clinical Frailty Scale \>\=4 and \<\=7\.
- •\- Diagnosis of:
- •Untreated systolic hypertension, i.e. office systolic blood pressure \>\=150
- •mmHg without antihypertensive treatment, or;
- •Uncontrolled systolic hypertension, i.e. office systolic blood pressure \>\=150
- •mmHg despite antihypertensive treatment.
- •\- Will be starting (untreated) or adding (uncontrolled) antihypertensive
- •treatment in the near future for (further) reducing systolic blood pressure by
- •\>\=10 mmHg while reaching a treatment target of office systolic blood pressure
Exclusion Criteria
- •\- Unable to provide signed and dated informed consent form.
- •\- Mentally incompetent subjects (e.g. due to dementia) as assessed by a
- •\- Currently enrolled in another interventional study targeting either blood
- •pressure and/or cerebral blood flow.
- •\- Cardiovascular event within the past 3 months.
- •\- Severe renal disease (eGFR \<40 ml/min).
- •\- Known secondary cause of hypertension that causes safety concerns.
Outcomes
Primary Outcomes
Not specified
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