NL-OMON51539招募中不适用
The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderly - BLUEBERRY
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 65 至 99（—）
入选标准
- •- Age >=70 years.
- •- Clinical Frailty Scale >=4 and <=7.
- •- Diagnosis of:
- •Untreated systolic hypertension, i.e. office systolic blood pressure >=150
- •mmHg without antihypertensive treatment, or;
- •Uncontrolled systolic hypertension, i.e. office systolic blood pressure >=150
- •mmHg despite antihypertensive treatment.
- •- Will be starting (untreated) or adding (uncontrolled) antihypertensive
- •treatment in the near future for (further) reducing systolic blood pressure by
- •>=10 mmHg while reaching a treatment target of office systolic blood pressure
- •<=140 mmHg, with the indication of primary or secondary prevention of vascular
- •events, judged by the treating physician (geriatrician or primary care
- •- Able to understand and perform study related procedures.
排除标准
- •- Unable to provide signed and dated informed consent form.
- •- Mentally incompetent subjects (e.g. due to dementia) as assessed by a
- •- Currently enrolled in another interventional study targeting either blood
- •pressure and/or cerebral blood flow.
- •- Cardiovascular event within the past 3 months.
- •- Severe renal disease (eGFR <40 ml/min).
- •- Known secondary cause of hypertension that causes safety concerns.
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