NL-OMON33986
Completed
Not Applicable
Medication induced blood pressure reduction; assessment of cerebral perfusion and cognition in hypertensive elderly - MBRACE
niversitair Medisch Centrum Sint Radboud0 sites60 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- high blood pressure
- Sponsor
- niversitair Medisch Centrum Sint Radboud
- Enrollment
- 60
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Systolic hypertension grade II\-III ( Systolic BP \>\=160mmHg) as measured according to JNC\-7 protocol
Exclusion Criteria
- •Systolic blood pressure \>220mmHg
- •Indication for urgent treatment of HT
- •Contra\-indication for MRI including claustrophobia
- •Contra\-indication for anti\-hypertensive medication used (Chlorthalidone, Amlodipine, Valsartan)
- •Renal failure requiring dialysis
- •Atrial fibrillation
- •A life expectancy of less than a year
- •Disabling stroke
- •Impairment by any cause prohibiting participation as mentioned by the general practitioner
- •Diabetes Mellitus
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Not Applicable
The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderlyhigh blood pressurehypertension10057166NL-OMON51539Radboud Universitair Medisch Centrum12
Active, not recruiting
Phase 1
The effects of blood pressure lowering on cerebral blood flow in older adults with high blood pressureHypertensionTherapeutic area: Diseases [C] - Cardiovascular Diseases [C14]EUCTR2022-001283-10-NLRadboud University Medical Center12
Not yet recruiting
Phase 4
Combination low dose blood pressure lowering treatment for patients with untreated hypertensioACTRN12617001533381George Medicines12
Completed
Not Applicable
Blood pressure lowering effect of one compound tablet replacement as two tablets of angiotensin 2 receptor blocker(ARB) and calcium channel blocker(CCB)the hypertensive patient who has taken ARB and CCBJPRN-UMIN000008360Department of Cardiovascular Medicine, Okayama Univesity Graduate School of Medicine, Dentistry and Pharmaceutical Sciences200
Completed
Not Applicable
Study on the effect of blood pressure suppression by single intake of test foodsHealthy AdultsJPRN-UMIN000053620Healthcare Systems Co., Ltd.4