To study the effect of steroid use during treatment of severe Covid 19 on steroid axis function during 6 month post covid period.
Not Applicable
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
- Registration Number
- CTRI/2021/05/033799
- Lead Sponsor
- Prof Dr Jayanthy Ramesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
diagnosed moderate or severe Covid 19 by RTPCR or Rapid Antigen Test(RAT) or HRCT thorax, admitted, treated and discharged from CSR Block, King George Hospital.
Those patients who were hospitalised and have received steroid treatment for less than 14days.
Those who give consent to participate in the study
Exclusion Criteria
Pregnant individuals
Patients receiving glucocorticoids for any indication prior to hospital admission
K/c/o primary/secondary adrenal insufficiency/ cortisol excess states
Patients with Chronic kidney disease, Chronic liver disease, Coronary artery disease , Cerebrovascular accident
Smokers/ Chronic alcoholism
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hypothalamo pituitary axis suppression, demonstrated by <br/ ><br> ACTH stimulated cortisol less than 18 mcg/dlTimepoint: 3 months and 6 months
- Secondary Outcome Measures
Name Time Method to coreelate between disease severity and HPA axis suppressionTimepoint: 3 month and 6 month