The effect of a collagen matrix on periodontal regeneration in intrabony defects - a randomised, controlled, clinical study
Not Applicable
Recruiting
- Conditions
- K05.3Chronic periodontitis
- Registration Number
- DRKS00020809
- Lead Sponsor
- niversitätsmedizin Mainz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Minimum Age of 18 years
- Periodontitis patients
- at least on intrabony defect with a intraosseous part of 3 mm on a single rooted tooth or a smooth surface of a multi-root tooth without furcation involvement
-good oral hygiene - under 25% Plaque after non-surgical therapy
Exclusion Criteria
- Sign of an acute infection
- Previous surgical intervention in the planned operating area
- Uncontrolled diabetes mellitus (HbA1c> 7)
- Pregnancy or breastfeeding
- Patients with a known allergy to collagen
- Long-term cortisone therapy
- Autoimmune diseases
- Radiation in the operating area
- Unhealed malignant systemic diseases (e.g. leukemia, carcinomas, etc.)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical attachment gain after 6 and 12 months
- Secondary Outcome Measures
Name Time Method After 6 and 12 months:<br>probing depth reduction (mm)<br>bleeding on probing reduction (%)<br>radiologic bone fill (%)<br><br>After 2-7-14 days: <br><br>Early healing index (EHI - Wachtel et al.)