Bio-Oss Collagen grafting and the periodontal attachment effects following extraction of mesioangular, impacted third molars in medically healthy and periodontally sound 18 - 35 year old adults.

The University Of Queensland0 个研究点目标入组 42 人开始时间: 2020年4月20日最近更新: 2023年8月21日

适应症

试验速览

阶段: 4 期
状态: 已完成
发起方: The University Of Queensland
入组人数: 42

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

Periodontal defects are associated with impacted wisdom teeth on the distal aspect of the second molar. These defects have been shown to persist even after wisdom tooth extraction. The study aimed to examine the additional periodontal healing benefits of grafting with Bio-Oss Collagen at the time of extraction. The patients recruited had severe pre-existing periodontal defects. The results showed no statistically significant bony healing improvement when grafting was performed. This was consistently shown when examined both two-dimensionally and three-dimensionally on the cone-beam CT scans. The study is limited by the high dropout rates and small sample size.

研究设计

研究类型: Interventional
分配方式: Randomised controlled trial
主要目的: Treatment
盲法: Open (masking not used)

入排标准

年龄范围: 18 Years 至 35 Years（—）
性别: All

入选标准

•One or two unerupted mandibular third molars that are Class I or II and Position B or C on the Pell and Gregory scale with a Horizontal or Mesioangular (10-80 degrees) of the Winter classification
•Evidence of radiographic bone loss of more than 5mm from the cementoenamel junction to the crest of the alveolar bone on the distal aspect of the distal root of the adjacent second molar at time of initial examination due to an impacted wisdom tooth
•Able to tolerate extraction procedure: surgeon will determine this parameter
•Medically fit and well. Classified as American Society of Anaesthesiologist (ASA) Class I patient as a normal, healthy patient. (no medical illness e.g. diabetes, not smoking, low alcohol intake)
•Aged 18 – 45 years old

排除标准

•Impacted third molars that are disto-angular impacted or require extensive surgery
•Patient has a history of diagnosed periodontitis disease (more than 2mm of clinical attachment loss)
•Patient currently has periodontal disease in any aspect of the mouth except periodontal breakdown associated with impacted third molars (mandibular or maxillary)
•Patient has lost more than 2mm of clinical attachment due to non-periodontal reasons
•Pathology that requires more than just extraction and primary wound closure
•Plaque index of 40% or more (indicating poor oral hygiene)
•Patients unwilling to return for all periodontal review appointment

研究者

发起方

The University Of Queensland

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