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临床试验/CTRI/2024/12/078817
CTRI/2024/12/078817尚未招募不适用

Evaluation of antibacterial activity of some Ayurvedic medicinal plants-based drug w.s.r to Urinary tract infections (UTIs)

Maharashi Patanjali Sanskrit Sansthan Bhopal1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年1月8日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
Recovery of urinary tract infection

研究概览

简要总结

Uncomplicated Lower urinary tract infection is the most common infections which are faced by human beings in this era. Recent reports show that UTI is more affecting the women in the age group of 15-44 than men. E.coli causes 80 % of uncomplicated UTI. Most of the studies done in high- or middle-income countries revealed that other pathogens (secondary pathogens) such as Klebsiella species, Enterobacter, Proteus species usually found in study participants with complicated UTI. All these symptoms of the disease closely resemble one among the diseases mentioned in Ayurveda under Mutravaha-srotho-dushti-vikaranamedMutrakruchra. Mutravaha-srotas is closely involved with Bastimarma, as it is one among the critical Trimarma where the Prana is said to be having its Ashrayasthana So, the management of this disorder has higher therapeutic value.  In Modern medicine, Antibiotics used for urinary tract infections. Antibiotics have their limitations like the development of resistance to the microorganisms, reinfection and relapses. Antimicrobial resistance adversely affects the outcome of community- and hospital-acquired infections in developing countries. So, to solve this problem, it is highly relevant to search for an alternative treatment which is both effective and economical. therefore we have selected present study and Ayurvedic plant-based drug which are effective in in vitro antibacterial activity study as well as safe in in vivo animal experiments, those Ayurvedic plant-based drug will be jointly used to evaluate the role of Ayurved medicines in the management of  urinary tract infection

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Uncomplicated UTI.

排除标准

  • complicated UTI other disease with urinary tract infection by pathogens other than bacteria.

结局指标

主要结局

Recovery of urinary tract infection

时间窗: 4 weeks

次要结局

  • complete Recovery of urinary tract infection(8 weeks)

研究者

发起方
Maharashi Patanjali Sanskrit Sansthan Bhopal
申办方类型
Other [research project]
责任方
Principal Investigator
主要研究者

Dr Kanhaiyalal Sharma

Govt Autonomous Ayurved college and Hospital Gwalior

研究点 (1)

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