MedPath

Comparison of analgesic effect between celecoxib and loxoprofen after orthopedic surgery

Not Applicable
Completed
Conditions
Patients undergoing orthopedic procedures and being given general anesthesia, but not undergoing epidural anesthesia, iv-PCA, or nerve block anesthesia
Registration Number
JPRN-jRCT1091220149
Lead Sponsor
Okabayashi Masanao
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
56
Inclusion Criteria

Patients undergoing orthopedic procedures and being given general anesthesia
Patients able to understand this study, and able to agree by themselves

Exclusion Criteria

Patients undergoing epidural anesthesia, iv-PCA, or nerve block anesthesia
Patients who have peptic ulcer, renal dysfunction(serum creatinine: male>1.5 female>1.2), who has been angina, cardiac infarction, or heart failure.
Patients who cannot understand VAS score

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Compare VAS score between celecoxib and loxoprofen group 2 hours after surgery, 4 hours after surgery, and 1hour after the next day's breakfast
Secondary Outcome Measures
NameTimeMethod
Compare rescue dose of analgesics, and side effects between celecoxib group and loxoprofen group
© Copyright 2025. All Rights Reserved by MedPath