Comparison of celecoxib versus acetaminophen as pre-emptive analgesics for the management of post operative pain after impacted mandibular third molar surgery

Phase 2

• Conditions: Condition 1: Third molar surgery. Condition 2: Pain. Condition 3: Celecoxeb.; Impacted teeth; Pain, unspecified; Other nonsteroidal anti-inflammatory drugs [NSAID]; K01.1; Y45.3

• Registration Number: IRCT20230714058773N4
• Lead Sponsor: Armed forces institute of dentistry CMH Rawalpindi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Male and female aged from 17 to 50 years old
Patients with at least one impacted mandibular third molar that is indicated for surgical extraction and also confirmed by periapical radiographs including mesioangular, distoangular, horizontal and vertical impactions
Patients with no intake of analgesic and anti-inflammatory drugs for 1 week.

Exclusion Criteria

Patients with conditions in which the use of NSAIDs and COX-2 inhibitors is contraindicated.
Patients with serious diseases like liver, kidney and cardiovascular diseases
Pregnant or nursing women
Patients with ulcers or bleeding in the digestive tract.
Patients who are unable to express subjective discomfort symptoms.
Patients with periodontal disease involving the adjacent teeth

Study & Design

• Study Type: interventional
• Study Design: Not specified