evaluation of adding celecoxib to treatment of mood disorder patients receiving electroconvulsive therapy
Not Applicable
- Conditions
- mood disorde.bipolar affective disorder/ depressive disorderF30-F39
- Registration Number
- IRCT201201247202N2
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Inclusion Criteria: diagnosis of mood disorder according to DSM IV TR criteria by a psychiatrist. Exclusion Cirteria: Patients with Hypersensetivity to celecoxib or other NSAIDs, Patients with rheumatologic disease, Organic Brain Syndrome, Severe Medical Conditions (cardiovascular disorders, hepatic, renal, respiratory, gasterointestinal), diabetes, patients undegoing treatment with of other NSAIDs or corticosteroides, receiving ECT in the past 2 months, hearing or talking problem and pregnanant patients were excluded.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in inflammatory factors. Timepoint: baseline, after ECT 1,3,6. Method of measurement: serum sample.;Change in cognition and memory. Timepoint: baseline, after ECT 1,3,6,. Method of measurement: MMSE,WMS and Stroop.
- Secondary Outcome Measures
Name Time Method Efficacy. Timepoint: baseline. after ECT 1,3,6. Method of measurement: Hamilton, YMRS.