Effect of celecoxib and ibuprofen versus placebo on pain after laparotomy in drug dependence
Phase 2
- Conditions
- Pain.Unspecified pain
- Registration Number
- IRCT201411269014N50
- Lead Sponsor
- Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 114
Inclusion Criteria
(a) age of 18 to 60 years; (b) candidate for laparotomy; (c) drug dependence.
Exclusion criteria: (a) using analgesic during 8 hours before surgery; (b) during pregnancy of breastfeeding; (c) sensitivity to celecoxib, ibuprofen, or vitamin B; (d) affected with cardiovascular diseases, renal diseases, liver diseases, and gastrointestinal diseases; (e) alcohol abuse.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measuring the pain severity. Timepoint: 1 and 6 hours after surgery. Method of measurement: using VAS scale.
- Secondary Outcome Measures
Name Time Method umber of narcotic or analgesic used. Timepoint: during the 6 hours after surgery. Method of measurement: by checking medical record.