A randomized comparative study of Celecoxib and Limaprost alfadex on the patients with lumber spinal stenosis for the effectiveness for symptoms and QO
- Conditions
- umbar spinal stenosis
- Registration Number
- JPRN-UMIN000004825
- Lead Sponsor
- niversity of Tsukuba, Course of life-style related disorders donated by JA Ibaraki Public Welfare Federation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 134
Not provided
1.Congenital lumbar spinal stenosis 2.Operation for lumbar spinal stenosis before three months 3.Indication for operation 4.Taking NSAIDs, Limaprost and Steroids before a week 5.Exclusion criteria a)ASO and below 0.9 of ABI b)Cerebral infarction c)Gait disturbance with Knee and hip osteoarthritis d)Diabetes (HbA1c>10% or diabetic neuropathy) 6. Severe low back pain and vertebral body fracture 7. Severe systemic past history such as heart, liver or kidney disease 8. Peptic ulcer 9. Severe abnormal symptom of blood 10. Pregnant or intend to become pregnant during the study period 11. History of hypersensitivity to Limaprost, celecoxib and sulfonamide 12. Aspirin-induced asthma 13. Patients who were recognized unsuitable for this study by primary physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Zurich claudication questionnaire
- Secondary Outcome Measures
Name Time Method 6-minute walk test JOA back pain evaluation questionnaire SF-36 Lumber extension test Safety: adverse events