Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Knee Pain
Not Applicable
Completed
- Conditions
- Osteoarthritis, Knee
- Interventions
- Device: Acupuncture
- Registration Number
- NCT03261505
- Lead Sponsor
- Massachusetts General Hospital
- Brief Summary
The aim of this study is to investigate brain response and connectivity changes evoked by video-guided acupuncture imagery treatment (VGAIT) and verum and sham acupuncture in knee osteoarthritis patients to elucidate the underlying brain mechanisms of mind-body interaction, imagery, and acupuncture.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 125
Inclusion Criteria
- Right-handed
- Knee osteoarthritis patients
- Ages 40 to 70 years old
Exclusion Criteria
- Any contraindications to MRI scanning (claustrophobia, metal implants)
- Current or past history of major medical, neurological, or psychiatric illness other than knee osteoarthritis (including high blood pressure, heart disorders, impaired elimination, stomach problems, major kidney or liver problems, bleeding problems, severe dehydration, history of diabetes, history of asthma or other respiratory condition)
- Pregnancy
- Non fluent English speaker
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description VGAIT Acupuncture - VGAIT Control Acupuncture - Real Acupuncture Acupuncture - Sham Acupuncture Acupuncture -
- Primary Outcome Measures
Name Time Method fMRI signal increases 4 days; Sessions 2-5
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Athinoula A. Martinos Center for Biomedical Imaging
🇺🇸Charlestown, Massachusetts, United States