Amino acid bioavailability in healthy older adults after bolus intake of high protein oral nutritional supplements
Completed
- Conditions
- Sarcopenia
- Registration Number
- NL-OMON24110
- Lead Sponsor
- utricia Research – Centre for Specialised Nutrition
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
1. Age 65 years or older
2. BMI from 20 through 30 kg/m2
Exclusion Criteria
1. Any gastrointestinal (GI) disease that interferes with GI function
2. Known renal or hepatic failure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome parameter in this study is the Leucine Cmax [μmol/L] (product A compared to product B).<br />
- Secondary Outcome Measures
Name Time Method The secondary outcome parameters in this study are comparison of product A and B on:<br /><br>• Leucine iCmax [μmol/L], iAUC [μmol/L*min] and t½ iAUC [min]<br /><br>• Essential aminoacids Cmax [μmol/L], iCmax [μmol/L], iAUC [μmol/L*min] and t½ iAUC [min]<br /><br>• Total sum aminoacids Cmax [μmol/L], iCmax [μmol/L], iAUC [μmol/L*min] and t½ iAUC [min]<br /><br>• Adverse events and (Gastro-Intestinal) tolerance questionnaire<br />