NCT02084069已完成3 期
Atrovastatin for Preventing Atrial Fibrillation Following Open Cardiac Valve Repair
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Atrial Fibrillation Incidence After Open Cardiac Valve Repair
研究概览
简要总结
The purpose of the investigation is to determine whether Atrovastatin as anti-inflammatory agent can be effective in preventing from atrial fibrillation incidence in patients whom undergone open cardiac surgery for their heart valve repair.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 25 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Greater than 25 y/o
- •No occurrence of intra- or post-operative cardiopulmonary arrest
- •Not consuming drugs affecting atrial rhythm
- •Having sinus rhythm before surgery
- •Lack of paroxysmal atrial fibrillation history
- •Only undergo heart valve surgery
- •Lack of considerable heart ischemia needed atorvastatin use
- •Routine cares in ward, post-operative ward, and intensive care unit were done
排除标准
- •Lesser than 25 y/o
- •History of atrial fibrillation
- •History of taking anti-arrhythmic drugs
- •History of implementing pacemakers
- •Severe heart failure
- •Renal failure
- •Hepatic failure
- •Severe pulmonary diseases
- •Heart block or bradyarrhythmia
- •Routine cares in ward, post-operative ward, and intensive care unit were not done
- •Performing concomitant cardiac surgery except valve repair
- •Having considerable heart ischemia needed atorvastatin use
研究组 & 干预措施
Treatment
Active Comparator
Atorvastatin 40 mg once daily from 3 days before surgery up to five days after surgery
干预措施: Atorvastatin (Drug)
结局指标
主要结局
Atrial Fibrillation Incidence After Open Cardiac Valve Repair
时间窗: Within 5 days after open cardiac valve repair
次要结局
未报告次要终点
研究者
研究点 (1)
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