Capsaicin-Evoked Pain in Patients With CRPS
Completed
- Conditions
- CRPS (Complex Regional Pain Syndromes)
- Registration Number
- NCT00468390
- Lead Sponsor
- Danish Pain Research Center
- Brief Summary
To evaluate the effect of capsaicin in patients with Complex Regional Pain Syndrome.
- Detailed Description
Primary outcome parameters: Capsaicin-induced pain and inflammation.
Secondary outcome parameters: Peripheral sensory and autonomic function.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Age: 18 or older.
- Pain in arm or hand > 3 months.
- Diagnosed with CRPS acc. to diagnostic research criteria (Harder et al., 2005)
- Inclusion of healthy subjects: age-, gender-, and BMI-matched.
Exclusion Criteria
- Other significant disease affecting the parameters measured, including cardiovascular disease.
- Treatment with anticholinergics, sympathomimetics and parasympathomimetics, and alpha- and beta-adrenergics.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie capsaicin-induced pain in CRPS patients as studied in NCT00468390?
How does capsaicin-evoked pain assessment compare to standard-of-care diagnostic methods for CRPS?
Are there specific biomarkers that correlate with capsaicin-induced inflammation in complex regional pain syndrome?
What adverse events are associated with capsaicin application in CRPS studies and how are they managed?
How do capsaicin studies in NCT00468390 contribute to understanding peripheral sensory dysfunction in CRPS?
Trial Locations
- Locations (1)
Danish Pain Research Center, Aarhus University Hospital
🇩🇰Aarhus, Denmark
Danish Pain Research Center, Aarhus University Hospital🇩🇰Aarhus, Denmark