Surface EMG Testing on Swallowing in EoE Patients

Recruiting

• Conditions: Eosinophilic Esophagitis (EoE)

• Registration Number: NCT07156357
• Lead Sponsor: Mayo Clinic

Brief Summary

Evaluating swallowing food with surface electromyography (EMG) machine in patients with Eosinophilic Esophagitis

Detailed Description

Evaluating surface electromyography (sEMG) assessment of swallowing and bolus preparation in patients with Eosinophilic Esophagitis (EoE).

Study Timeline

• Status Verified: 2025-08
• Study Start: 2025-08-04
• Study First Submitted: 2025-08-15
• Study First Submitted QC: 2025-09-04
• Last Update Submitted: 2025-09-04
• Study First Posted: 2025-09-05
• Last Update Posted: 2025-09-05
• Primary Completion: 2026-06
• Study Completion: 2027-06-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Controls

  • Normal video swallow or score of 0 for dysphagia on ESSAI questionnaire
  • absence of dysphagia
  • age >18 EoE participants
  • Documentation of EoE diagnosis by histologic criteria,
  • >15 eos/hpf on most recent esophageal biopsy
  • age >18

Exclusion Criteria

• Abnormal baseline video swallow
• lack of MSK coordination to eat test meal
• underlying neuromuscular disorder.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Preparatory phase time	Through study completion an average of 2 days	Comparison of preparatory phase between cohorts

Secondary Outcome Measures

Name	Time	Method
Time difference in swallow initiation	Through study completion an average of 2 days	Time difference in swallow initiation between fiberoptic endoscopic evaluation of swallowing (FEES) vs sEMG

Trial Locations

Locations (1)

Mayo Clinic; 🇺🇸 Rochester, Minnesota, United States