NCT06854146进行中（未招募）不适用
Study on the Development and Prognosis of Gastric Cancer Based on Environmental Factors and Macrogenome
Dong Peng1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2024年11月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Overall Survival (OS)
研究概览
简要总结
The objectives of this study were to clarify how environmental factors such as air pollution affect the occurrence and development of gastric cancer; to identify patient-specific macrogenomic markers of gastric cancer; and to investigate the mechanism of gastric cancer development based on environmental factors and macrogenomic data.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age ≥ 18 years;
- •patients with preoperative diagnosis of gastric cancer confirmed by pathologic biopsy;
- •no chemotherapy, radiotherapy, targeted and immunotherapy, etc. before enrollment;
- •willing to participate in the study and sign the informed consent form;
- •complete clinical data.
排除标准
- •concurrent primary malignant tumor other than gastric cancer;
- •patients with systemic diseases, such as severe cardiopulmonary;
- •insufficiency, that affect the choice of treatment plan;
- •not suitable for enrollment as assessed by the investigator;
- •incomplete clinical data.
结局指标
主要结局
Overall Survival (OS)
时间窗: From date of diagnosis until the date of death from any cause or or loss to follow-up, whichever came first, assessed up to 60 months
Description: Time from diagnosis to death from any cause, measured via medical records and follow-up interviews. Unit: Months
次要结局
- Gut microbiome composition differences assessed by shotgun metagenomic sequencing(Tissue samples collected intraoperatively, sequencing completed within 1 week post-surgery.)
研究者
Dong Peng
Principal Investigator
First Affiliated Hospital of Chongqing Medical University
研究点 (1)
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