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临床试验/ISRCTN13100451
ISRCTN13100451已完成未知

Hypertension- and glycaemia-lowering effects of a grape-pomace-derived seasoning in patients and healthy volunteers. Interplay with the gut microbiome

Institute of Food Science Research0 个研究点目标入组 31 人开始时间: 2020年11月27日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
31

研究概览

简要总结

2022 Results article in https://doi.org/10.1039/D1FO03942C (added 13/01/2022)

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • Current participant inclusion criteria as of 05/11/2021:
  • Presenting with at least two of the following risk factors of metabolic syndrome:
  • 1. Hypertension (systolic BP =130 mmHg or diastolic BP >85 mmHg)
  • 2. Hypercholesterolemia (HDL colesterol <40 mg/dl in men and <50 mg/dl in women)
  • 3. Hypertriglyceridemia (triglycerides >150 mg/dl)
  • 4. Increased fasting plasma glucose (>100 mg/dl)
  • 5. Increased waist circumference (>94 cm in men and >80 cm in women)
  • Healthy participants:
  • Presenting with normal values of the parameters mentioned above.
  • Previous participant inclusion criteria:
  • Participants have to present at least two of the following risk factors of metabolic syndrome:
  • 1. Hypertension (systolic BP =130 mmHg or diastolic BP >85 mmHg)
  • 2. Hypercholesterolemia (HDL colesterol <40 mg/dl in men and <50 mg/dl in women)
  • 3. Hypertriglyceridemia (triglycerides >150 mg/dl)
  • 4. Increased fasting plasma glucose (>100 mg/dl)
  • 5. Increased waist circumference (>94 cm in men and >80 cm in women)

排除标准

  • 1. Serious cardiovascular disease
  • 2. Antibiotic intake up to 3 months before the study
  • 3. Endocrine and gastrointestinal disorders
  • 4. Addiction to drugs or alcohol
  • 5. Restrictive diets (vegetarians, vegans)

研究者

发起方
Institute of Food Science Research

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