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Clinical Trials/NCT02068261
NCT02068261
Unknown
Phase 2

Computerized Working Memory Training in Adults With Substance Abuse and Executive Function Deficits: A Randomised Controlled Trial.

Örebro Läns Landsting1 site in 1 country100 target enrollmentJanuary 2014

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Substance Abuse
Sponsor
Örebro Läns Landsting
Enrollment
100
Locations
1
Primary Endpoint
Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA).
Last Updated
10 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse and attention problems.

Detailed Description

The primary aim of this study is to examine the effects of 5 weeks of computerized working memory training on substance abuse. Secondary aims are to explore whether effects are mediated by changes in executive functions and/or moderated by personality. Also, effects on measures of psychosocial functioning, depression, anxiety and attention will be explored. Follow-up assessment will be conducted at 6 months post training.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
December 2016
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Örebro Läns Landsting
Responsible Party
Principal Investigator
Principal Investigator

Rickard Ahlberg

Clinical psychologist, doctoral student.

Örebro Läns Landsting

Eligibility Criteria

Inclusion Criteria

  • Treatment seeking adults with substance abuse and executive function deficits.

Exclusion Criteria

  • Acute intoxication or abstinence symptoms of any substance.
  • Psychosis.

Outcomes

Primary Outcomes

Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA).

Time Frame: Baseline and at 25 weeks

Secondary Outcomes

  • Change from baseline in Adult Self Report (ASR; ASEBA) Internalizing index.(Baseline and at 25 weeks)
  • Change from baseline in focused attention measured with performance on Conners Continuous Performance Test-II (CCPT-II).(Baseline and at 25 weeks)
  • Change from baseline in Adult Self Report (ASR; ASEBA) Externalizing index.(Baseline and at 25 weeks)
  • Change from baseline in verbal working memory measured with performance on Digit span.(Baseline and at 25 weeks)
  • Change from baseline in Adult Self Report (ASR; ASEBA) Attention problems scale.(Baseline and at 25 weeks)
  • Change from baseline in Adult Self Report (ASR; ASEBA) Adaptive functioning scales.(Baseline and at 25 weeks)
  • Change from baseline in Executive functioning measured with Behavior Rating Inventory of Executive Function-Adult (BRIEF-A).(Baseline and at 25 weeks)
  • Change from baseline in visual working memory measured with performance on Span board.(Baseline and at 25 weeks)
  • Change from baseline in vigilance measured with performance on Conners Continuous Performance Test-II (CCPT-II).(Baseline and at 25 weeks)
  • Change from baseline in reading speed measured with performance on Reading speed in Diagnostic Reading and Writing Test (DLS; Swedish version).(Baseline and at 25 weeks)

Study Sites (1)

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