Efficacy of statin therapy on arterial wall inflammation in patients with Chronic Kidney Disease
Recruiting
- Conditions
- chronic kidney disease stages 3 and 4, defined by a eGFR of 15-60 ml min
- Registration Number
- NL-OMON22577
- Lead Sponsor
- Academical Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 17
Inclusion Criteria
1. Aged 50 years or older
2. CKD stages 3 and 4 (eGFR: 15-60 ml/min per 1.73m2)
Exclusion Criteria
1. Malignant diseases or any clinically significant medical condition that could interfere with the conduct of the study in the opinion of the investigator.
2. Standard contra-indications to 18F-FDG PET, and CT based on physicians experience and current practices
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.
- Secondary Outcome Measures
Name Time Method To assess differences in the innate immune system in patients with CKD before and after treatment with statins.