Role of the subthalamic nucleus for learning simple stimulus-response associations - a multi modal analysis using LFP and EEG data

Not Applicable

• Conditions: G20; Parkinson disease

• Registration Number: DRKS00020220
• Lead Sponsor: Carl von Ossietzky Universität OldenburgFakultät VI - Medizin und GesundheitswissenschaftenDepartment für Humanmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

Parkinson patients undergoing implantation of deep brain stimulation system at the Evangelisches Krankenhaus Oldenburg, followed by a period of time during which DBS leads remain externalized.

Moreover inclusion criteria encompass: Becks Depression Inventory < 25, Mattis Dementia Rating Scale > 130, Mini Mental State > 23

Exclusion Criteria

acute psychiatric disorders, hearing disability/deafness, increased risk of infection

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary goal is to determine whether stimulus-response associations are represented within the activity of the subthalamic nucleus. In order to assess these hypothesis we will measure and analyze behavioral-, EEG-, and local field potential data.<br><br>

Secondary Outcome Measures

Name	Time	Method
The secondary goal is to determine whether activity of the nucleus subthalamicus is predictive of the successful selection of a correct association. In order to assess these hypothesis we will measure and analyze behavioral-, EEG-, and local field potential data.<br>