A Comparative clinical study to evaluate the clinical efficacy of Jatiphaladi Lepa and Lodhradi Lepa along with Khadirashtak Kwatha in the management of Mukhadushika with Special referance to Acne Vulgaris

Ayurveda being the most ancient science which believes in  three pillars, (vata,pitta and kapha )dosha , seven types of dushya and three types of Mala. The equilibrium state of normalcy of all the factors is considered as Swastha. If  one of these factor gets vitiated it creates disequilibrium with the swastha ,And when such vitiation occurs at specific part of the body or organ the symptoms are also observed with respect to  that part of the body or organ.

In such a way when Vata,kapha and Rakta dushya gets vitiated, small or medium sized eruptions appear over the face it is  diagnosed as Mukhadusika ( Mukh=Face And Dushika means which causes disfigurement over the facial surface) and these appear mostly in adolescent young age ,hence mentioned as Tarunyapitika in  texts ( Acne Vulgaris) . Sometimes there may be meda accumulated inside the eruptions hence in Ashtang Hriday mukhadusika are described as Medogarbha[1], which looks like shalmali kantak hence the appearance of   mukhadusika are compared with shalmali kantak. [2]

Acne Vulgaris is most common disorder of Pilosebaceous glands which commonly affects the hair folicles found over the face[3]

Acne vulgaris mainly affects the age group of 15year to 30 years. 90% of Adolescent boys and 80-85% of adolescent Girls get affected with Acne Vulgaris[3] There are some endocrinological disorders also causing acne Vulgaris  (Hypothyroidism, PCOS in females, During menstruation in females due to surge of oestrogen hormone) and so on.

There are some predisposing factors regarding Lifestyle, such as, Disturbed sleep, Consumption of junk, oily foods, etc. can cause acne over the face. Some environmental factors such as Hot and Humid Atmosphere can also aggravate the diasease. Moreover Excessive use of Cosmetic products, Oil based Local applications  causes acne over the face.

The presentation of Acne Vulgaris is mainly characterised in the form of Papules, pustules and Nodules( painful or painless).

In Ayurvedic texts, acne vulgaris is mentioned as Mukhadushika / Tarunyapitika and Medogarbha in which the Vatadosha, Kaphadosha and Rakta dushya are vitiated .Mukhadushika is described under Kshudra rogas in Sushrut Samhita[4], Madhav nidan[5], Ashtang sangraha[6], Ashtang Hriday[7] and Sharangdhar samhita[8]. There are no as  such  specific etiological factors are described in  texts regarding mukhadushika.

As Perfect skin is, for most people, a distant dream. Chronic skin conditions typically are not curable in western system of medicine, but they can be manageable using Ayurvedic therapies and by paying close attention to our lifestyle. This case is a example of Mukhadushika like skin disease can be managed with Ayurvedic therapy. The combination of drugs selected ( Manjishtha,Patol,Sariva, Musta, Kutaki, Amalragandhi haridra, Patha )[9] will act over the pathological aspect of the disease breaking pathology as whole with maintaining the asthestic value.

Need of study

It is a celebrity topic in dermatology and it is not only  harming physically but mentally and socially too….   Hence it is matter of concern!!!

We all have seen college going students literally going into depression , trying out all the possible ways to treat acne. Hence some or the other way they land up in buying costlier medicines. Majority of  acne case if left untreated it may turn into scar formation or hyperpigmentation (PIH). only Local applications ,creams  gives temporary relief but may lead to recurrence. Ayurvedic formulations given internally can act over the targeted dosha ( vata, kapha and Rakta) in order to break the pathology and treating disease as whole.

  Group of patients: Group I:         No. of Patients: 44

Treatment: Jatiphaladi Lepa once a day over the acne.

 Group II**:**      No. of Patients: 44

Treatment:  Jatiphaladi Lepa over the acneand Khadirashtak kwatha(20ml) orally twice a day.

Investigations

Blood CBC ,ESR,Lipid Profile, BSL Fasting and Post prandial

SUMMARY & CONCLUSION

The work will be summarized to make final conclusions. Observation of result will be concluded with statistical analysis under the heading conclusion with explanation at the end of whole research. The data collected from CRF will be subjected to statistical analysis, appropriate statistical tests will be applied to the data generated and significance of improvements will be studied.