Oxytocin Effects on the Tolerance of Infidelity

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Drug: oxytocin treatment; Drug: placebo treatment

• Registration Number: NCT02733237
• Lead Sponsor: University of Electronic Science and Technology of China

Brief Summary

To investigate whether intranasal oxytocin (40 IU) treatment can influence the tolerance of infidelity in males and females.

Detailed Description

In a double-blind, between-subject, placebo controlled design, investigators plan to investigate the effect of oxytocin treatment on the tolerance of infidelity. Male and female subjects would firstly see a neutral face of the opposite sex presented with a sentence descried their fidelity or infidelity behavior (sexual or emotional) in a relationship. Next the participant will rate the attractiveness, likability and trustworthiness of each individual, and whether they would like to have a short/long relationship with him/her. After that there will be some implicit attitude tasks to test their implicit attitude towards potential partners exhibiting previous fidelity or and infidelity.

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2016-03-30
• Primary Completion: 2016-04
• Study First Submitted QC: 2016-04-08
• Study First Posted: 2016-04-11
• Study Completion: 2016-05
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-02
• Last Update Posted: 2017-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• Healthy subjects without past or current psychiatric or neurological disorders

Exclusion Criteria

• history of head injury;
• pregnant,menstruating,taking oral contraceptives
• medical or psychiatric illness.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
male oxytocin group	oxytocin treatment	male subjects with oxytocin treatment
male placebo group	placebo treatment	male subjects with placebo treatment
female oxytocin group	oxytocin treatment	female subjects with oxytocin treatment
female placebo group	placebo treatment	female subjects with placebo treatment

Primary Outcome Measures

Name	Time	Method
attitude towards fidelity and infidelity of potential mate.	1 hour	attitude is measured by the rating scores for likability, attractiveness and trustworthiness

Trial Locations

Locations (1)

China, Sichuan; 🇨🇳 Chengdu, Sichuan, China