CTRI/2024/06/068267尚未招募4 期
Sedation in upper GI endoscopic procedures A comparison between propofol and dexmedetomidine
The Institute of Post Graduate Medical Education and Research1 个研究点 分布在 1 个国家目标入组 96 人开始时间: 2024年6月17日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 96
- 试验地点
- 1
- 主要终点
- Intravenous dexmedetomidine can be a suitable alternative for sedation in comparison to intravenous propofol.
研究概览
简要总结
Diagnostic and therapeutic endoscopy is a routine and often challenging procedure taken up by gastroenterologists to perform different clinical procedures and diagnostic test. Patients often require moderate to deep sedation in order to tolerate manipulation of the endoscope. In this study we will compared the adequacy of sedation, hemodynamic stability, obtundation of airway reflex, breakthrough awakening and post procedure recovery and recall between propofol and dexmedetomidine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients between 18 to 60 years either gender.
- •No major comorbidity.
排除标准
- •Patients refusing consent.
- •Patients with major cardio respiratory comorbidities.
- •Hypersensitivity to study drugs.
- •Previously failed upper GI endoscopic procedures.
- •Patients with ongoing upper GI bleed.
- •Patients with airway abnormalities.
结局指标
主要结局
Intravenous dexmedetomidine can be a suitable alternative for sedation in comparison to intravenous propofol.
时间窗: During Upper GI endoscopic procedures.
次要结局
- Assessment of peri procedural hemodynamic stability in upper GI endoscopic procedures while using intravenous dexmedetomidine & intravenous propofol.(During Upper GI endoscopic procedures.)
- Assessment of peri procedural obtundation of airway reflex in upper GI endoscopic procedures while using intravenous dexmedetomidine & intravenous propofol.(During Upper GI endoscopic procedures.)
研究者
Arnab Roy
Institute Of Post Graduate Medical Education and Research Kolkata
研究点 (1)
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