Veranderingen in het hartritme bij patiënten met reuma en bij mensen met een voorlopervorm van reuma (gekenmerkt door gewrichtsklachten en positieve reuma-antistoffen).
Recruiting
- Conditions
- RAreumarheumatoid arthritis
- Registration Number
- NL-OMON23052
- Lead Sponsor
- AMC amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
1. 18-85 years;
2. Individuals with pre-clinical arthritis (n=60):
Exclusion Criteria
All subjects:
1. Cardiovascular disease, such as ischaemic heart disease, cardiomyopathy, cardiac arrhythmia, cerebrovascular events, hypertension;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HRV in subject with pre-clinical arthritis, patients with active RA and healthy subjects. HRV is a reflection of the autonomic nervous system and these results will be related to clinical presentation and physical examination of the subjects.
- Secondary Outcome Measures
Name Time Method The 24-hour HRV will be analysed for day and night differences.