The relationship between intraoperative dexmedetomidine, HMGB1 protein levels, and cognitive dysfunctio
Not Applicable
- Conditions
- Not Applicable
- Registration Number
- KCT0006497
- Lead Sponsor
- Ewha Womans University Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 128
Inclusion Criteria
Patients undergoing a non-cardiac surgery under general anesthesia who are aged over 64
Exclusion Criteria
Emergency operation, organ transplantation surgery, cardiac surgery
Liver failure, renal failure.
American Society of Anesthesiologists (ASA) physical classification 4 or 5
Underlying dementia, Parkinson's disease
Unable to communicate or unclear mentality
Refuse to write informed consent
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HMGB1 blood level;Mini cog test result
- Secondary Outcome Measures
Name Time Method Incidence of POCD