Colonoscopic surveillance using narrow-band imaging in patients with hyperplastic polyposis syndrome (HPS)
Recruiting
- Conditions
- Hyperplastic polyposis syndrome, hyperplastic polyp
- Registration Number
- NL-OMON28466
- Lead Sponsor
- Academic Medical Center (AMC), Department of Gastroenterology
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 22
Inclusion Criteria
All patients presenting, or under surveillance at the Endoscopy Department of the AMC with:
1. >10 HPs found at colonoscopy, or
Exclusion Criteria
Exclusion criteria are
1. History of inflammatory bowel disease,
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The sensitivity of WLE will be compared to that of NBI for the detection of polyps and cancer in the colon. The sensitivity of each technique will be calculated as the number of lesions detected during the first inspection, divided by the total number of lesions detected by both inspections.
- Secondary Outcome Measures
Name Time Method Furthermore, the surface pit pattern of the detected lesions on NBI will be used to obtain the overall accuracy (representing sensitivity and specificity) of this technique, by using the histological diagnosis as the gold standard diagnosis. Moreover, the prevalence and distribution of HPs, SAs, MPs and adenomas in this patient population will be described