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Endoscopic surveillance using narrow-band imaging in patients with hyperplastic polyposis syndrome (HPS): A multi-centre cohort study.

Conditions
Hyperplastic PolyposisSyndromeNarrow Band Imaging
Registration Number
NL-OMON23826
Lead Sponsor
Academic Medical Center, University of Amsterdam
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
52
Inclusion Criteria

All HPS patients, defined as having:

1. ≥5 HPs/SSAs proximal to the sigmoid colon of which 2 are greater than 10mm in diameter or;

Exclusion Criteria

1. Patients carrying a germline mutation in the MutYH (biallelic) or APC gene and individuals who have undergone a total colonic resection;

2. History of inflammatory bowel disease;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Polyp miss-rates of NBI vs. HRE.
Secondary Outcome Measures
NameTimeMethod
The diagnostic accuracy of NBI-VPI vs. HRE-VPI for the differentiation of polyps.
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