Endoscopic surveillance using narrow-band imaging in patients with hyperplastic polyposis syndrome (HPS): A multicentre cohort study

• Conditions: polyps; tumor; 10018018

• Registration Number: NL-OMON34162
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 72

Inclusion Criteria

All patients presenting, or under surveillance at the endoscopy department of the AMC with:
1) > 20 HPs found at colonscopy, or
2) > 5 HPs proximal to the sigmoid colon, or
3) Any number of HPs occuring proximal to sigmoid colon in an individual who has a first-degree relative with HPs

Exclusion Criteria

1) History of inflammatory bowel disease 2) severe coagulopathy 3) age less than 18 years and 4) insufficient bowel preparation ( < 90% of colonic mucosa visible)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Polyp miss-rates of NBI vs. HRE<br /><br>2) The diagnostic accuracy of NBI-VPI vs. HRE-VPI for the differentiation of<br /><br>polyps</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none</p><br>