Effect of drospirenone on apoptosis and anti-proliferation in ectopic endometrial stromal cells: an in vitro study

Phase 1

• Conditions: Endometriosis; Ectopic endometrial stromal cells; Drospirenone; Apoptosis

• Registration Number: TCTR20221129005
• Lead Sponsor: Siriraj research fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-29
• Study Completion: 2024-01-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

Women age 18-45 years
Diagnosis of endometriotic cyst and undergoing
ovarian cystectomy or SO or BSO
No hormonal treatment in last 3 months

Exclusion Criteria

Gynecologic malignancy
Failed endometrial sampling
On medication with effect to endometrial cell proliferation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anti-proliferation and apoptosis 24 hours Flow cytometry

Secondary Outcome Measures

Name	Time	Method
Dose of drospirenone 24 hours Flow cytometry