Effects of low-dose sevoflurane on infant motor evoked potentials

Not Applicable

• Conditions: Spinal; D013122; Spinal diseases

• Registration Number: JPRN-jRCT1041230094
• Lead Sponsor: Kojima Taiki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-10-18
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

Spinal surgery patients scheduled for intraoperative MEP less than 1 year old

Exclusion Criteria

Patients with preoperative lower limb motor dysfunction (incomplete or complete paralysis)
Patients who should refrain from using inhalation anesthetics (sevoflurane)
(e.g., neuromuscular disease, history (including suspicion) of malignant hyperthermia)
Patients who cannot use propofol (e.g., egg white allergy)
Patient and family refusal for any reason
Intraoperative circulatory instability due to anesthetics administered by intraoperative intervention
If the anesthesiologist in charge (independent of the research team) determines that the protocol anesthetic agents do not provide adequate depth of anesthesia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage (%) of attenuation of the TOP to BOTTOM values of the MEP potential waveform (continuous variable) in the upper extrimities.

Secondary Outcome Measures

Name	Time	Method
Percentage (%) of attenuation of the TOP to BOTTOM values of the MEP potential waveform (continuous variable) in the lower extrimities.