A Study on Primary hypothyroidism for finding efficacy of Homoeopathic medicines

Phase 3

Not yet recruiting

• Conditions: Other specified hypothyroidism,

• Registration Number: CTRI/2025/05/086783
• Lead Sponsor: Dr Asla V c

Brief Summary

This study is an Open label randomized clinical trial involving the comparative study of therapeutic benefts between LM and Centesimal potencies of constitutional homoeopathic medicine in primary hypothyroidism. Patient who are satisfying diagnostic criteria  are randomly allocated into 2 groups by computer generated  random number table method.First group will be given constitutional homoeopathic medicines in centesimal potencies and for  2 nd group medicines  will be given in  LM potencies. Primary outcome are measured by Free T4 and TSH Values at baseline and after 3 months. Secondary outcome measured by WHOQOL-Bref Questionare score at baseline after 3 months. Final calculation of data analyzed by independent t test or Mann whitney U test.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-06
• Last Update Posted: 2025-09-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 36

Inclusion Criteria

Cases that fulfill the diagnostic criteria Women of age in between 15 to 60 years TSH greater than 4.50 mIU per L with Free T4 below the reference value where reference value in between 0.8 to 1.8 ng per dl.

Exclusion Criteria

TSH less than 0.4 mIU per L with symptoms of hyperthyroidism TSH greater than 4.5 mIU per L Above the reference value Patients with any other severe systemic illness pregnant and lactating mothers patients with severe hypothyroidism suspected myxedema cases and severe Immunodeficiency diseases like AIDS thyroid neoplasia diagnosed cases of pituitary tumuors like TSH oma.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The outcome of treatment will be assessed by TSH and Free T4 value	The outcome of treatment at baseline after 3 months

Secondary Outcome Measures

Name	Time	Method
Change in quality of life of patients determined by WHOQOL-Bref questionnaire score	Base line and after 3 months of treatment

Trial Locations

Locations (1)

Government Homoeopathic Medical College Kozhikode; 🇮🇳 Kozhikode, KERALA, India

Government Homoeopathic Medical College Kozhikode

🇮🇳Kozhikode, KERALA, India

Dr Asla Vc

Principal investigator

9745364432

aslavc44@gmail.com