ess Bleeding by Omitting Aspirin in Non-ST-segment Elevation Acute Coronary Syndrome Patients - LEGACY

Amsterdam UMC0 个研究点目标入组 3,090 人开始时间: 2022年2月2日最近更新: 2024年2月26日

适应症

试验速览

暂无简介。

•Patients aged 18 years or older are eligible for inclusion if all of the following criteria are met:
•- Clinical diagnosis of NSTE-ACS (i.e. NSTEMI or unstable angina)
•- Successful PCI (according to the treating physician)
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 1545
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range 1545

•Patients who meets any of the following criteria will be excluded from participation:
•- Known allergy or contraindication for aspirin or all commercially available P2Y12-inhibitors (i.e. ticagrelor, prasugrel and clopidogrel)
•- Concurrent use of oral anticoagulants (e.g. because of atrial fibrillation)
•- Ongoing indication for DAPT at admission (e.g. due to recent PCI or ACS)
•- Planned surgical intervention within 12 months of PCI
•- Pregnant or breastfeeding women at time of enrolment
•- Participation in another trial with an investigational drug or device

发起方

Amsterdam UMC