Aspirin in noncardiac surgery - ASINC

• Conditions: Patients with cardiovascular risk factors undergoing elective non-cardiac surgery of high or intermediate risk.

• Registration Number: EUCTR2004-005136-76-SE
• Lead Sponsor: Professor Christina Eintrei,Institution of Medical & Health, Section of Anesthesiology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-03-07
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 660

Inclusion Criteria

Patients with at least one of the following risk factors will be included:

·Patients with known or suspected ischemic heart disease
·Medical history of congestive heart failure
·Renal impairment (S-creatinine > 170 µmol·ml-1).
·History of cerebrovascular accident
·Insulin treated Diabetes Mellitus.

To be included the patient must undergo surgical procedures of high or intermediate risk. In this study patients undergoing the following procedures will be possible to include:·
Laparatomier med förväntad operationstid > 1 timme inkluderande:
·Esofagus kirurgi
·Pancreas kirurgi
·Ventrikel kirurgi
·Lever kirurgi
·Gallvägskirurgi (ej okomplcerade cholecystektomier)
·Intraabdominell endokrin kirurgi
·Tarm kirurgi
·Fundoplicatio/Crusplastik

Urologisk kirurgi inkluderande:
·Prostata kirurgi, bade open samt transuretral
·Nefrektomi
·Cystektomi

Ortopedisk protes kirurgi, inkluderande:
·Höft artroplastik
·Knä artroplastik
·Axel artroplastik

Gynekologisk kirurgi, inkluderande
·Abdominell hysterektomi
·Transabdominell gynonkologisk kirurgi

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Exclusion criteria
·Patients undergoing diagnostic procedures
·Patients with unstable CAD
·Patients with incompensated congestive heart failure
·Patients in shock.
·Patients with pacemaker.
·Patients under 18 years.
·Patients with an allergy to aspirin
·Patients with a known history of ulcer
·Patients on Warfarin or Clopidogrel

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified