Comparison of effect of Dexmedetomidine and Esmolol during Anaesthesia of Brain Tumour Surgery .

Phase 1

• Conditions: Health Condition 1: G94- Other disorders of brain in diseases classified elsewhere

• Registration Number: CTRI/2019/06/019907
• Lead Sponsor: IPGMER SSKM HospitalKolkata

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.AGEâ??20-55 YRS

2.SEXâ??either sex

3.GCSâ??14-15

4.SURGERYâ??elective intracranial surgery of a supratentorial tumour under general anaesthesia

5.ASAâ??1 to 2

6.BMI-- <30

7.HR-- >60/ min

8.BPâ??MAP > 80 mm hg

9. Patients or patient party willing to provide written informed consent

Exclusion Criteria

1.Predicted difficult intubation

2.Preoperative beta blocker therapy, alpha-methyldopa,clonidine or other alpha2 agonist

3.Contraindication to beta blocker administration

4.Any history of drug abuse

5.Systemic illness such as considerable hepatic ,renal failure

6.Preoperative neurodeficit or aphasia

7.Known allergy to any of study drug

8.Uncontrolled htn, bronchial asthma, dysarrythmia including af, heart failure, cardiovascular complication, 2nd or 3rd degree heart block

9.Any pre operative haemodynamic instability

10.Pregnency

11.Any patient with difficult intubation requiring more than 20 seconds to intubate

12.Any prolonged operation ( duration > 3 hour )

Study & Design

• Study Type: Interventional
• Study Design: Not specified