HCV, HBV, HIV Testing During Consultation With Anesthesiologist
- Conditions
- HBVHivHCV
- Interventions
- Procedure: HCV, HBV, HIV tests
- Registration Number
- NCT04286347
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Brief Summary
The aim of the study is to assess the feasibility of HCV, HBV, HIV testing (according to the national guidelines) during consultation with Anesthesiologist before a planned surgery in Lariboisiere Hospital, Paris, France. The feasibility will be the number of tested patients divided by the number of patients who should have been tested according to the national guidelines (for each virus).
- Detailed Description
The aim of the study is to assess the feasibility of HCV, HBV, HIV testing during consultation with Anesthesiologist before a planned surgery in Lariboisiere Hospital, Paris, France.
The national guidelines recommend at least one HIV testing during life and, more recently, one HCV testing during life to eradicate HCV infection. HBV testing is recommended in patients coming from high prevalence countries, IVDU, prisoners, patients with multiple sexual partners.
The feasibility will be the number of tested patients divided by the number of patients who should have been tested according to the national guidelines (for each virus).
HIV testing will use finger-stick whole blood (FSB) INSTI® HIV-1 \& HIV-2 Rapid Antibody Test FSB (BioLytical TM Laboratories Inc., Richmond, B.C., Canada), with a sensitivity 99% \[96.3-99.7\] and a specificity 99.3%.
HCV testing will use finger-stick whole blood (FSB) Oraquick® HCV test, with a sensitivity and a specificity 99.1 and 100% respectively.
HBV testing will use finger-stick whole blood (FSB) Vikia® HBs Ag test, bioMérieux with a sensitivity and a specificity 96.5 and 99.9% respectively.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 363
- patient ≥ 18 years-old
- planned surgery in Lariboisiere Hospital, Paris, France
- able to give written informed consent for testing
- proposed to be tested for HIV and HCV if no previous testing found in the medical record
- proposed to be tested for HBV if the patient belong to a high-risk group: high prevalence area (Asia, sub-Saharan Africa, French Indies, East and South Europe, North-Africa, Middle-East, India, Pakistan, South-America), IVDU, prisoners, unprotected sexual intercourses.
- patient < 18 years-old
- emergency surgery
- unable to give written informed consent for testing: psychiatric diseases, neurologic diseases, ...
- a previous testing for HIV and HCV found in the medical record and no obvious risk factor after previous testing
- the patient does not belong to a high-risk group for HBV
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description HCV, HBV, HIV testing HCV, HBV, HIV tests All patient ≥ 18 years-old with a next planned surgery in Lariboisiere Hospital, Paris, France, able to give written informed consent for testing will be proposed to be tested for HIV and HCV if no previous testing found in the medical record and will be proposed to be tested for HBV if the patient belong to a high-risk group: high prevalence area (Asia, sub-Saharan Africa, French Indies, East and South Europe, North-Africa, Middle-East, India, Pakistan, South-America), IVDU, prisoners, unprotected sexual intercourses.
- Primary Outcome Measures
Name Time Method Feasibility of HCV, HBV, HIV testing Day 0 : during initial consultation, up to 1 hour Feasibility (assessed by the number of tested patients divided by the number of patients who should have been tested according to the national guidelines (for each virus)) of HCV, HBV, HIV testing during consultation with Anesthesiologist before a planned surgery in Lariboisiere Hospital, Paris, France
- Secondary Outcome Measures
Name Time Method Acceptability of HCV, HBV, HIV testing Day 0 : during initial consultation, up to 1 hour Acceptability (number of patients who accept to be tested divided by the number of patients who should have been tested according to the national guidelines (for each virus) of HCV, HBV, HIV testing during consultation with Anesthesiologist before a planned surgery in Lariboisiere Hospital, Paris, France
Acceptability of being treated (for each virus) for the patients who have been tested positive for HCV and/or HBV and/or HIV, by questionning during Day 0, after the initial consultation Acceptability of being treated (for each virus) for the patients who have been tested positive for HCV and/or HBV and/or HIV during consultation, by direct questionning, with Anesthesiologist before a planned surgery in Lariboisiere Hospital, Paris, France.
Trial Locations
- Locations (1)
Lariboisière
🇫🇷Paris, France