MedPath

Integrating HCV and HIV Screening During the Era of HIV Antigen Testing

Not Applicable
Completed
Conditions
HIV
Hepatitis C
Interventions
Behavioral: Questionnaire
Procedure: Rapid finger stick
Procedure: Venipuncture
Registration Number
NCT02869776
Lead Sponsor
Boston Medical Center
Brief Summary

The objective of this proposal is to develop an optimal testing strategy for HCV and HIV in high prevalence settings, such as detoxification centers with a large proportion of young injection drug users. The latest venipuncture testing will be compared to rapid finger stick testing for HCV and HIV. Outcomes for each strategy among individuals admitted at a short-term drug detoxification center will be determined.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Age greater or equal to 18
  • All clients admitted to BTC with a history of drug or alcohol use
  • Individuals who self-report as being HIV and HCV non-infected within the past 6 months or having unknown status
  • Participants providing contact information of two family members or friends
  • Individuals signing a medical records release form for the referral site (Boston Medical Center)
  • English speaking
Exclusion Criteria
  • Individuals unable to provide informed consent
  • Individuals with a known history of HCV and/or HIV

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Rapid finger stickRapid finger stickHIV and HCV testing through rapid finger stick. Behavioral questionnaires will also be administered.
Standard venipunctureVenipunctureHIV and HCV testing through venipuncture. Behavioral questionnaires will also be administered.
Rapid finger stickQuestionnaireHIV and HCV testing through rapid finger stick. Behavioral questionnaires will also be administered.
Standard venipunctureQuestionnaireHIV and HCV testing through venipuncture. Behavioral questionnaires will also be administered.
Primary Outcome Measures
NameTimeMethod
Number of participants who receive HIV test resultswithin 5 days (by the time of discharge from the detoxification center)

The number of participants who receive HIV test results by the time they are discharged from the detoxification center

Number of participants who receive HCV test resultswithin 5 days (by the time of discharge from the detoxification center)

The number of participants who receive HCV test results by the time they are discharged from the detoxification center

Secondary Outcome Measures
NameTimeMethod
Number of participants who have HCV treatment initiatedby six months

The number participants who have HCV treatment initiated

Number of participants who link to HCV careby three months

The number of participants who are seen for an HCV visit

Number of participants who have fibrosis staging performedby three months

The number participants who have fibrosis staging performed

Number of participants who reach sustained virologic responseby twelve months

The number participants who reach sustained virologic response

Number of participants who HIV RNA testingby 3 months

The number participants who have HIV RNA testing

Number of participants who achieve HIV viral suppressionby 6 months

The number participants who achieve HIV viral suppression

Number of participants who link to HIV careby 3 months

The number participants who are seen for an HIV visit

Number of participants who have antiretroviral treatment initiatedby 3 months

The number participants who initiated antiretroviral treatment

Number of participants who have HCV RNA testingby three months

The number of participants who have HCV RNA testing performed

Number of participants who have CD4 testingby 3 months

The number participants who have CD4 testing

Trial Locations

Locations (1)

Boston Medical Center

🇺🇸

Boston, Massachusetts, United States

© Copyright 2025. All Rights Reserved by MedPath