Personalised hemodynamic modeling of arteriovenous grafts

Recruiting

• Conditions: Arteriovenous graft stenosis; vascular access stenosis; 10038430; 10003184; 10047066

• Registration Number: NL-OMON54588
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

- Patients receiving vascular access surgery at Maastricht UMC+
- Patients receiving a first ipsilateral upper arm arteriovenous graft
(straight and loop configurations and different graft materials can be included)
- Patients 18 years and older and mentally competent

Exclusion Criteria

- Patients with a life expectancy of less than one year
- Patients with central venous stenosis at baseline
- Patients with contraindications for magnetic resonance imaging (MRI)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>We will provide a descriptive evaluation of blood flow patterns and derived<br /><br>parameters in our hemodynamic models, which is common practice in studies on<br /><br>computational fluid dynamics simulations in vascular access. The secondary<br /><br>study parameters are the degree of stenosis at which the graft is at risk of<br /><br>thrombosis according to the computational fluid dynamics model, and the<br /><br>associations between hemodynamic parameters and future stenosis development.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>