Effects of Zeolive on hepatotoxicity

Phase 1

• Conditions: Acetaminophen Poisoning, Hepatotoxicity.; Poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics, undetermined intent

• Registration Number: IRCT20211213053375N1
• Lead Sponsor: Toxicological Research Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Consume more than 7.5 grams of acetaminophen
Taking acetaminophen with unknown amount and high liver enzymes
Toxic levels of acetaminophen according to the Rumack–Matthew nomogram

Exclusion Criteria

Previous history of any liver disease
Sensitivity to zeolite compounds

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ormal levels of liver enzymes. Timepoint: Primary outcome is measured following the administration of Zeolive and 14 days after that. Method of measurement: Liver enzyme levels will be measured using the Mindray BS-800.;Normal range of prothrombin time (PT). Timepoint: Primary outcome is measured following the administration of Zeolive and 14 days after that. Method of measurement: Prothrombin time will be determined using the succeeder SF-8100.