Dynamic indices of fluid responsiveness and tissue perfusio

Completed

• Conditions: Hypovolemia; low central blood volume; 10003184

• Registration Number: NL-OMON37776
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Healthy subjects between 18 and 80 years old.

Exclusion Criteria

Cardiac arrythmias and absence or insufficient quality of the Doppler and/or NIRS signals.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary end-points of this study are cerebral blood flow, cerebral/muscle<br /><br>oxygenation and arterial oxygen saturation. These parameters reflect tissue<br /><br>perfusion/oxygenation. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The study parameters which are measured to investigate the influence on the<br /><br>primary end-points are:<br /><br>- Blood pressure<br /><br>- Stroke volume<br /><br>- Heart rate<br /><br>- Cardiac output<br /><br>- Tidal volume<br /><br>- Breathing frequency<br /><br>- Tilt angle </p><br>