The influence of cocaine and cannabis on impulsivity.

• Conditions: cannabiscocaineimpulsivityimpulsiviteitgenotyperinggenotypingdopamineCOMTDBH

• Registration Number: NL-OMON25495
• Lead Sponsor: ZonMW

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1. Regular use of cannabis and cocaine;

2. Good physical and mental health;

Exclusion Criteria

1. Pregnancy or lactation;

2. Cardiovascular abnormalities as assessed by standard ECG;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The influence of cocaine and cannabis on impulsivity modulated by COMT and DBH genotypes. Genotyping of DBH will be performed before inclusion, COMT after testing.

Secondary Outcome Measures

Name	Time	Method
Outcomes on: <br /><br>1. Matching familiar figures;<br /><br>2. Stop-signal task;<br /><br>3. Tower of London;<br /><br>4. CTT/DAT;<br /><br>5. Attentional Switch task;<br /><br>6. Prospective memory task;<br /><br>7. Cued Go/NoGo task.<br>