Pilot study on conditioning cortisol levels and its psychophysiological effects
Completed
- Conditions
- Op dit moment wordt het onderzoek bij gezonde proefpersonen uitgevoerd. Uitkomsten uit deze lijn van onderzoek bieden in de toekomst mogelijk nieuwe handvatten voor verklaringsmodellen en therapeutische interventies voor aandoeningen waarbij een verstoring in de functie van de HPA-as optreedt.Niet van toepassing
- Registration Number
- NL-OMON37492
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
healthy, female, premenopausal, 18 - 45 years of age
Exclusion Criteria
Severe psychiatric and/or somatic diseases, symptoms of infection, use of medication (including oral contraceptives), recent stressful life event
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters of the pilot study are the feasibility of the design<br /><br>(e.g., most useful assessment points for the psychophysiological assessments,<br /><br>safety, drop-out). Variance of endogenous cortisol levels at the evocation<br /><br>phase as well as correlations between cortisol levels at the evocation phase<br /><br>and at baseline in the experimental group will also be assessed, in order to<br /><br>enable a founded power analysis for the main study. In the main study, the main<br /><br>study parameters will be endogenous cortisol levels and psychophysiological<br /><br>parameters (e.g., in response to cognitive and psychosocial tasks) at the<br /><br>evocation phase. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>