A Check-list Including Lung Ultrasound for ED Patients With ARF

Not Applicable

Completed

• Conditions: Acute Respiratory Failure
• Interventions: Other: check-list including lung ultrasound

• Registration Number: NCT04791241
• Lead Sponsor: Centre Hospitalier Metropole Savoie

Brief Summary

The aim of the study is to evaluate if a check-list including lung ultrasonography can help to identify the etiology of the acute respiratory failure of patients managed at the emergency room.

Adult patients admitted to the emergency room for acute respiratory failure will be offered the study. The emergency physician will perform a systematic examination using a checklist, including pulmonary embolism prediction scores, structured clinical examination and lung ultrasound, in order to establish a diagnostic hypothesis.

A diagnostic hypothesis will be made after completion of the checklist. The emergency physician can perform additional examinations and treatment after completion of the checklist.

The final diagnosis will be checked by an adjudication committee which will have all the documents established during the emergency room consultation and any hospitalization following this hospitalization.

The main outcome will be the concordance rate between the diagnosis after the check-list and the final diagnosis.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-02-22
• Study Start: 2021-03-03
• Study First Submitted QC: 2021-03-08
• Study First Posted: 2021-03-10
• Primary Completion: 2022-01-03
• Study Completion: 2022-01-04
• Status Verified: 2022-06
• Last Update Submitted: 2022-06-20
• Last Update Posted: 2022-06-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

• Patient with acute respiratory failure table (SpO2 90% in ambient air or need more than 3 L/min of oxygen to have SpO2 > 92% AND/OR signs of respiratory struggle sign AND/OR respiratory rate control > 25 cycles/minute AND/OR cyanosis)
• Over 18 years old

Exclusion Criteria

• Pregnant, Parturising or Breastfeeding Women
• Patient who has already participated in the study in the previous 7 days

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
check-list with ultrasound	check-list including lung ultrasound	check-list including lung ultrasound for the management of patients with acute respiratory failure at the emergency department during the COVID-19 era

Primary Outcome Measures

Name	Time	Method
Agreement between the etiology retained after using the checklist and the diagnosis retained by an adjudication committee after analysis of the entire patient file.	1 month after inclusion	The adjudication committee will meet all 35 inclusions to determine the diagnosis of each patient after analysis of the complete anonymized file which will be provided by locol investigator one month after inclusion.

Secondary Outcome Measures

Name	Time	Method
Comparison of treatments introduced after completion of the checklist and after the other additional examinations performed at the emergency room	at one day	all treatments delivered after the completion of the checklist and after complementary exams will be collected and classified into therapeutic families (antibiotics, diuretics).
Collection of additional examinations possibly performed in the emergency unit after the completion of the checklist	at one day	All additional examinations performed after the completion of the checklist will be collected
Analysis of the diagnosis retained after the checklist in patients with a final diagnosis of COVID-19; analysis of the final diagnosis in patients with a diagnosis of COVID-19 evoked after the checklist	One month after inclusion	The adjudication committee will meet periodically after analysis of the complete anonymized file to check the COVID diagnosis.
Collection of treatments started only after completion of the checklist and verification of its suitability for the diagnosis selected	at one day	All the treatments started only after completion of the checklist wil be collected prospectively and their appropriateness will be checked.
Delay between completion of the checklist and obtaining the results of any other examinations	At one day	Time between the completion of the checklist and obtaining the last result of the other examinations performed at the emergency room (except for bacterial culture)

Trial Locations

Locations (3)

CHUGA; 🇫🇷 Grenoble, France

CH Annecy Genevois; 🇫🇷 Annecy, France

Centre Hospitalier Metropole Savoie; 🇫🇷 Chambéry, France