Bactericidal Effect in Periodontal Treatment using Laser and Photosensitizer
- Conditions
- Periodontitis
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
(1)Healthy adult with periodontal disease as follows Those who have teeth with residual periodontal pocket of 5 mm or more If there are some teeth with a residual periodontal pocket of 5 mm or more, select based on the following criteria
- Deeper pocket teeth
- Upper jaw teeth
- More mesial teeth
- Right tooth
Those who have a stable occlusion
(2) Patients aged 20 years or older
(3) Patients who can visit the hospital for 2 consecutive weeks (4) Patients who have given written consent to participate in this study
(1) Patients taking antibiotics within the last 3 months (2) Patients who have taken or are taking anti-cancer drugs within 6 months (3) Patients with a history of allergies to Indocyanin Green (4) Patients with a history of allergies to shellfish (5) Pregnant, lactating and potentially pregnant or willing women (6) Patients taking immunosuppressive agents and corticosteroids within the last 3 months (7) Other patients who are judged by the research responsible / shared doctor to be inappropriate as research subjects
Study & Design
- Study Type
- Interventional
- Study Design
- parallel assignment
- Primary Outcome Measures
Name Time Method - Reduction rate of live bacterial number before and immediately after procedure.
- Secondary Outcome Measures
Name Time Method Change rate of red complex before and one week after procedure Change rate of red complex before and one week after procedure using real time PCR
Change of bleeding on probing before and one week after procedure Change of bleeding on probing before and one week after procedure
Comparison of live bacterial cell counts before and 1 week after procedure Comparison of live bacterial cell counts before and 1 week after procedure