The composition of the human intestinal MICROBIota in Anorexia Nervosa patients before and after weight gain compared with normal-weight participants (MICROBIAN)

• Conditions: anorexia nervosa; F50; Eating disorders

• Registration Number: DRKS00005124
• Lead Sponsor: niversitätsklinikum Tübingen, Innere Medizin VI, Psychosomatische Medizin und Psychotherapie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07-03
• Study Completion: 2013-08-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 110

Inclusion Criteria

Feemale patients and an age above 14 with anorexia nervosa (all subtypes) with an indication for hospitalization with the purpose to gain weight. Reference group: normal weight participants, matched for gender and age.

Exclusion Criteria

Exclusion criteria are physical, linguistic or intellectual limitations which do not allow the patients to collect a stool sample or to follow the instructions. The decision is made by the responsible neuropsychologist. Controls: The decision is made by the examiner. If written informed consent is not provided by the participant and/or the legal guardian, this is also an exclusion criterion.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome is the change oft the body mass index. Body weight ist assessed upon admission and prior to discharge using a calibrated scale.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are: 1) the change of body composition. Body composition is assessed upon admission and prior to discharge using a lipometer 2) the change of nutrition intake in kcal. Nutrition intake is assessed upon admission and prior to discharge using standardised 24 h food records.