A CLINICAL TRIAL TO STUDY THE EFFECT OF TWO DRUGS JAK INHIBITORS (TOFACITINIB) AND NSAIDS ON PATIENTS WITH AXIAL SPONDYLOARTHROPATHIES
Phase 2
- Conditions
- Health Condition 1: M450- Ankylosing spondylitis of multiplesites in spine
- Registration Number
- CTRI/2024/04/066083
- Lead Sponsor
- Dr Nilotpal Saikia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Diagnosed Cases of Ankylosing Spondylitis, 2. Patients with no Medical Contraindication, 3. Skeletally Mature Patients.
Exclusion Criteria
1. Age less than 18 years, 2. Patients with active infections (tb & other viral and bacterial infection), 3. Pregnant, Lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the clinical improvement between the two groups.Timepoint: To compare the clinical improvement between the two groups at 4 weeks, 8 weeks, 12 weeks.
- Secondary Outcome Measures
Name Time Method 1. To compare the efficacy of the drugs between two groups. <br/ ><br>2. To compare the incidence of side effects of the drugs between the two groups. <br/ ><br>3. To compare the ASAS 20/ ASAS 40 response between the two groups. <br/ ><br>4. To compare the improvement of ASDAS/BASDAI score between two groups.Timepoint: 1. 4, 8, 12 weeks <br/ ><br>2. 4, 8, 12 weeks <br/ ><br>3. 4, 8, 12 weeks <br/ ><br>4. 4, 8, 12 weeks