National Egyptian Network Pediatric Stroke and Hemiplegia Registry

• Conditions: Stroke With Hemiparesis; Perinatal Stroke; Focal Neurologic Deficits

• Registration Number: NCT02129491
• Lead Sponsor: Ain Shams University

Brief Summary

Our aim is to establish multi-center national Egyptian database of information about cerebrovascular stroke and hemiplegia in infants and children from 0 to 18 years of age.

Detailed Description

Aims: An open-ended multi-center, national Egyptian study to collect and analyze data for children with cerebrovascular stroke and hemiplegia .

Participants: Eligible infants and children with stroke and hemiplegia.

DESIGN: This study is a prospective cohort study.

Primary outcome measure: Initial acute stroke clinical and radiological presentation, recurrent stroke, mortality, and neurologic deficits in the acute stage, participants will be followed for the duration of hospital stay, an expected average of 6 weeks

Study Timeline

• Study Start: 2014-01
• Study First Submitted: 2014-04-15
• Status Verified: 2014-05
• Study First Submitted QC: 2014-05-01
• Last Update Submitted: 2014-05-01
• Study First Posted: 2014-05-02
• Last Update Posted: 2014-05-02
• Primary Completion: 2020-01
• Study Completion: 2021-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Focal neurological deficit of acute onset lasting greater than 20 minutes. And CT or MRI showing infarct in location consistent with neurological signs and symptoms
• Hemiplegia

Exclusion Criteria

1. Cerebral haemorrhage not associated with ischemic infarct.
2. Hypoxic ischemic event with diffuse or bilateral infarction alone.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival or neurologic deficit after acute cerebrovascular stroke.	participants will be followed for the duration of hospital stay, an expected average of 6 weeks	Children with acute stroke will be followed till either death or discharge from hospital, all clinical, radiological and therapeutic data will be collected.

Secondary Outcome Measures

Name	Time	Method
Long term neurological deficit	12 months	Post-stroke pediatric gross and fine motor function will be assessed.

Trial Locations

Locations (1)

Pediatric Department, Children's Hospital, Faculty of Medicine, Ain Shams University; 🇪🇬 Cairo, Abassia, Egypt